Nope. Anna never gets mentioned again. Besides, what's she gonna do? She's a kid whose eyes were scooped out of her head and is now being treated alongside her family who've now lost everything by professionals under state guard. No amount of suspension of disbelief could bring her back unless the author took a page out of the Shield hero and somehow made her a soul fragment of some evil god that has yet to be mentioned, but even that is unlikely given the story's tone.
Also, as for haters, no one specific is ever brought up, but it has been mentioned numerous times that half the nobility hate Streamer for being a commoner and out of jealousy for how much support he recieves. So much so that in chapter 74 (Volume 3), half the nobility of the Xandard Empire, another neighboring country to Rogias that specializes in their military but has rampant class discrimination and Mira's place of birth, stage a civil war against the current reigning empress who (surprise surprise) is also a Massive Streamer fan who's been proactive in implementing policies Kanata mentioned on stream (equality, anti-discrimination, etc.). But those that opposed her got quite literally curbstomped, partially because they were outnumbered by just about everyone, and partially because the empress is a cunning tactician, really freaking strong all-round (both-physically, mentally and magically) and is always informed of everything (and I mean EVERYTHING) that happens in the Empire. For example, in chapter 124 (Volume 4 and the latest chapter to date), after conversing with her ministers she casually chucks a sword into the ceiling, killing a spy that had been listening to her conversation while they were hiding like a ninja in disguise.