I wonder if the Witch of East knows that Runa can't use any skills/abilities if her mana is drained to zero, because if she knows it would be pretty cruel to put on another curse on Runa like a one where her mana drain down to zero all the time.
From what shown in previous chapter there was a machine to extract man juice out of men. They probably filled syringes with it, then women would use a syringe filled with man juice inside their private part.