Sacrificing Mirko at this point would be not clever for the in-universe logic. We as the reader have come to like Mirko a lot, but most of the main cast haven't interacted with her much, so the loss wouldn't have the biggest impact on them. Loosing Hawk would be the most logical as he has been really important story-wise.
Of course I hope all of them survive.
Small side-note, I just can't hear the name Stain anymore ...