Shino and Shoutaro is remind me with Nozomi and Taishi, not to mention the disappearance Minato is exactly like what the Shoutaro's nee-chan did.
Also, We can really see how shock is Shino when she saw Nozomi with other man, even the usually composed her is so flustered and blabering everything to Shoutaro(well, it means she trust him, maybe?)
Shino is currently in lost to where she belong, 'cause the one that she can called home aka her brother, already passed away. Then, Nozomi, who, might be a new home, a new family to her, might be leaving her all alone.
And, well I really looking forward to their relationship. Especially, of course, Shino and Nozomi.