Well~ it's interesting given that he, as the only observer within the box, is the only one knows that he's alive, but observers outside the box can't tell. At the same time, to be considered alive, does he need an external observer to acknowledge it? The definition of 'life' is also something that we humans arrived at arbitrarily, with plenty of things straddling the border between life and death. I guess that juxtaposition is ultimately where the series title comes from.
So minus the radiation and superposition aspects of the thought experiment, I actually think the analogy works a lot better here than how it's used in a lot of other contexts just because of the discussion about consciousness and observers.