Well, if Ippo DOESN'T come back to the ring... then the title is kinda pointless then.
Still, it seems he will be able to make a comeback, and this time, simply blowing past everyone he meets... until the last challenge. It will either be Miyata, beating him to the title first, so it will be pretty much the same kind of relationship they have had for some time... even if Ippo wins that, Ippo was always the challenger, and generally never the defender.
OR, it could be an expected(well, to me, at least) twist of irony, in which Ippo was able to get the world title first, making Miyata the challenger this time. Whether that match will be shown, or simply ending it where they are about to punch each other in the ring, I have no idea.