With regard to the quality of depicting achieving a dream and the sacrifices required, I think this is up there with Andre Agassi's autobiography Open. There are so few people in the world that will truly understand what achieving a dream means. Most people will never even get the opportunity. You have to be at least partially insane, as evidenced by Nikaidou's actions, and then you have to be in the position to even do it in the first place.
It's all made nearly impossible by the mere virtue of the fact that to give up a normal life to achieve a dream you have to be mad. You have to have some kind of drive beyond everyone else's drive, an obsession. You may have to give up everything a regular person wouldn't. It's clear Fukumoto understands this on a level beyond almost anyone else. And I get it... even if Nikaidou died without ever achieving anything, at least he would have given it his best shot. It might seem like a platitude -- who cares, if you're dead anyway -- but I'd rather know I tried.