* Reader settings stored in browser's local storage.
Open mangadex (any page), press F12, select the "Console" tab and copy-paste:
to fully reset reader settings.
Or you could do
Code:
copy(JSON.stringify(localStorage))
to copy your settings to clipboard and post them here for a bug report (do that before resetting them).
Did you try explicitly exiting your browser after clearing the cache (from browser menu)?
Extensions and userscripts could be the reason, try disabling extensions one by one and see how the reader behaves.
You have both Ublock Origin and ABP, which just slows down your browser. Choose one (Ublock is better) and enable additional regional filter lists in settings.