People here in the comments being negative about the wife should not be so quick to judge. We already in the beginning were suspicious of cheating, but then it turned out she wasn't. Most of our negative impression of her coming from something that was proven false aside, even the other negative aspects of her relationship with her husband could be recontextualised in the future.
Rather than just blaming the wife for everything and calling her toxic, it could just be a typical marriage slump where both people are at fault for bringing the relationship to this point, both are feeling the effects of it and both need to work for it if they want to restore the relationship.
I said this back in the first chapter (in a different comment section when this wasn't on Mangadex), but this manga has two paths it can take. Either it continues on the path of self-improvement where Ayase helps him improve his life and his troubled relationships as demonstrated in the first chapter (his colleagues, his daughter, his wife), but ultimately they never get together, cheating doesn't happen and Tamaki restores his relationship with his wife. Or the story commits to the relationship being unsalvageable/the wife being bad to justify Tamaki separating with her and making up with Ayase instead (hopefully with no substantial cheating involved).
Personally, I find the former to be the happier story and the more fulfilling solution to the problems presented at Chapter 1 (rather than just saying you should divorce your wife if you don't get along and looking for love elsewhere, resolving the problems that got you into the mess is better). I don't know if the story will commit to that idea, but I do find it to be the more thematically fitting one. Not sure what would happen to Ayase in that version, though, especially considering these chapters have established her actually crushing on Tamaki rather than solely wanting him for his body.