This Manga really goes against the mainstream, but I like it that the characters have some depth, they chose the way they want to be, even if that made them lose sth in return.
Theoretically yuu can still be with sato, I mean (s)he doesn’t mind yuu being a dude it seems. He is still that childhood friend and person he went on a date with.
Then again there’s nothing wrong with Yuu preferring to be with a female, nothing to blame, except the „love“.
It would have been a great arc to see them overcome the challenges and still end up together.