From the previous chapter, it sounds like the world is unraveling. We always thought it was weird how the Grey didn't appear to affect the planet, even with stuff like the Briefcase, as it was never mentioned after its chapters. But I guess it all has been falling apart after all. Just nobody was looking at it.
In chapter 221: Demolition Crew page 17 onwards, it's explained that the "Kuroiwa family" is responsible for taking in calamities, which turns them into curses. The Kuroiwa hold back all the gray.
Problem is, unless relieved of duty by the next Kuroiwa, they can't die, and our Kuroiwa, the one who's been issuing red cases, has been alive for several centuries.
That obviously wears a person down having to absorb all those calamities/gray matters for several centuries, which is a pretty big problem, cuz those curses and calamities start to leak.
That's what all the color cases are, curses, they may not necessarily be strong though some of the colors have tended to be pretty apocalyptic so far or involving deities of some kind. That could just be the effect of the wear and tear on Kuroiwa, and as a result stronger curses are getting released.
It's also interesting, but page 21, Kuroiwa mentions the previous "Kuroiwa" had been around for centuries, which affected it's ability to hold in curses. It makes me wonder if he's talking about the previous one in the Tomb, or if he's referring to the Kuroiwa we've been following so far. If it's the latter, then that means that the Kuroiwa are either clones, which I find unlikely, or the same person that's repeating this duty, but each new version is "fresh" and unaffected by time, kinda like starting a new save file or something.
It was manageable, because of a certain being reset the world for em but now it's unravelling as more and more god-entities start taking action while architect not give any do-over
There's the Designer too, but it's not moving anymore, either out of choice because it's satisfied with the future and no longer needs to rectify the timeline or because something got to it. Like maybe the God of Nothing.