Holiday Yasumi's Twitter Shorts - Ch. 1153 - If Something Like That Were Done to Me

Sickly Senpai
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Is it even possible to knock someone out IRL with only a cloth soaked in chloroform?

Yes, though it would take a couple minutes of prolonged contact to do so. And choloform can also be fatal if taken in too much, so it could just as easily kill them instead
Bingo. Chloroform fell out of favor as an anesthetic because the gap between the lower limit/ therapeutic effects and the upper limit/adverse effects is very small. Even during the mid-late 1800's when chloroform was given with specialized masks and careful dosage from doctors, about 1-in-1000 people anesthetized with it would drop dead from cardiac arrhythmia. If you have a large blob of it on a handkerchief and it's strong enough to knock someone out, they're probably not waking back up.

Also, today-I-found-out that the trope of it being a "magic knock-out drug used by criminals" (despite it being slow-acting IRL) goes back to at least 1865, as debunked in a The Lancet medical journal from that year:
Those journals seem, however, to have no doubt about the fact that a highwayman can, by shaking a handkerchief impregnated with chloroform under the nose of his victim, produce instantaneous insensibility. It is within the experience of medical men that anaesthesia by chloroform is not very quickly or very easily effected upon a non-consenting person, and that with the utmost resignation and good-will some five minutes or more are requisite to produce anaesthesia.
 
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Oh naw, that’s crazy. :huh:


When you play “marry, f@ck, kill” with your friend. But your friend always chooses the same person. :worry:
 
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Yes actually but it's not instant. It'll take more than 3 minutes and the clothe has to really be press on the nose to get inhaled.
Yeah as funny as it is to joke, the other person will generally know something's up within the first few seconds.

It was a quality that early anesthesiologists liked as it was a slow, easy procedure to induce unconsciousness rather than an "Oh no, they have suddenly stopped breathing" a minute after application. Which can be a risk for IV anesthesia, especially if it's a formula you've not taken into your body before.
 
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