Oh, I forgot another pair of characters who have gone through a lot of change since their introduction: it's easy to forget that our introduction to poor Lou/Louise probably gave all of us a bad impression, with the shadow half of the pair in particular coming off as vain and vapid.
I talked my mother into watching the anime a year or two ago, and she decided she didn't like or trust Ricky/Rick right from their introduction, and it was a bit of fun for me to realize that I'd forgotten how much he changed over time, coming off as sneaky, conniving, and unscrupulous at first, before we got to know him better (especially by the end of the Margaret/Maggie subplot and/or the flashbacks to before he got to Shadows House!)
The characters in this story are (not always, but often) a bit more complicated than they seem to be at first, especially those who start of as a bit off-putting or even villainous!
And, on a silently different track, since I was just thinking of the anime again and this last chapter reminded me that Maryrose/Rosemary and Barbie/Barbara had a thing about dancing, I just wanted to stop a moment to say that the end credits for the anime's second season are particularly beautiful - I enjoyed the anime all around, but this was especially well done: