I found it funny that his immediate instinct upon seeing a roach was "FOOD." Even if he's very familiar with the setting of the game, eating a roach would make most people uncomfortable at first. I wonder if his mentality will be a bit less human.
A bit random, but this "saint" Hermie Schultz that was introduced at the end has a face very similar to Schnee's.
Might just be a quirk of the art style, but I wonder if there's a connection there.
That 'congratulations' might be the first genuinely positive interaction we've seen between Carlo and the Duke. When Carlo initially left for the academy, it was just a terse farewell.