Consistent on all browsers for me as well, and for several days as well (specifically, since the DDOS alert came up on the 5th, so perhaps there's an association to it).
Most times I can't get past the first page of updates at all [As shown by the OP, all I get is a blank page for /updates/#/], and the first page randomly cuts short and takes a number of refreshes to load itself fully. The cover page [mangadex.org, rather than mangadex.org/updates] loads its list without issue, however.
Edit: Seems resolved.