Siscon Ani to Brocon Imouto ga Fuufu ni Nattara Shiawase Sugite Bakuhatsushisou - Oneshot

[furtadopires]

@Sullieman the author released another small chapter in his pixv.

Any chances to your mahou shoujo form bless us with a translation and wisdom?

 

[Sullieman]

@Sullieman the author released another small chapter in his pixv.

Any chances to your mahou shoujo form bless us with a translation and wisdom?

I have some good news, bad news, and a bit of extra info.
First, it's not a small chapter is a full 33 pages doujinshi with a whooping 16 pages of extra content.
Second, I might get it done but I don't think it would be anytime soon so it's better if you don't get your hopes up.
Lastly, the author is a woman, which might make it better for you. Some time ago she was doing streamings of her drawing at Twich, I haven't checked if she's still doing those though.

 

[furtadopires]

Lastly, the author is a woman, which might make it better for you.

Not a difference for me, but her brother probably likes it

 

[Y0UR_U53R]

I'm not even surprised that Kyuukei translated this.

 

[HAt_Sauce234]

Oh my.... I shouldn't so haphazardly pick random oneshots to read....

 

[adamb15]

aaHAHAHA
All right, not too shabby.

 

[Takuto96]

I like how people are talking about birth defects when they both mentioned one time near the ending of the original manga that they can't have a baby (and probably don't plan to) before they end up having seggs. Shizuku from Ani to Imouto no Shitai Shitai Shitai Koto on the other hand...phew.

There was art request session on Hano's twitch and one of the requests included the art of Ritsu and Uta with their baby. Hano started with a sketch but very soon dropped the idea due to various reasons. Mostly due limited time, but there was also another request of art with Ritsu and Ami getting alternate happy end. As Hano started drawing those, she ended having them side by side and eventually decided stop, because it "felt wrong", leaving those ideas possibly for another time. All she managed to draw is this:

(Ami happy end is left, Uta's baby end is right).

Anyway regarding Ritsu's and Uta's baby, according to Hano, at this point it's just her dream idea, so nothing guaranteed to happen, but baby's name could be possibly "Kanade" following music naming pattern that Ritsu's and Uta's own names have.

Extremely based of HanoHaru to share what-if fantasies like their children's names or alternate endings etc instead of like every other author that won't touch anything that's not canon/won't happen 🙏🙏

Does anyone have that art of HanoHaru drawing Uta pregnant though bc it's been mentioned thrice here but I couldn't find it on Twitter or smth

 

[smormu]

Birth defect incoming

The danger of inbreeding is more so in genetic disorders than birth defects.

Inbreeding between siblings greatly increases the chance of homozygousity for recessive genes. Harmful genes are usually recessive because that way they’re harder for natural selection to get rid of since they can be carried without harming the individual. In order for a recessive gene to be expressed you need a copy of it from both parents. If your parents are closely related then it is more likely for them to both have that recessive gene. Assuming that both parents are heterozygous for that harmful gene then the chance the child will have the disorder it causes Is 1/4.

Where inbreeding gets really bad is when you do it generation after generation. When you have a child you pass on only half of your genes. If you have another you aren’t guaranteed to pass on the opposite half, some of your genes probably won’t be passed on. Imagine a brother and sister having 2 children who then have 2 children and so on. Every generation some of the genes don’t get passed on and thus the genetic difference between them shrinks. Eventually everyone in this gene pool (more of a gene lane) will effectively be clones who are completely homozygous for everything and all harmful genetic disorders they still carry will be expressed.

 

[smormu]

@sirflimflam
Bro, they've hurt their parents when they eloped like that...

They didn’t really elope, they just moved out when they got older. They literally just went off to college together.

 

[havelmom]

props to this mangaka not backing down from her beliefs

 

[havelmom]

Birth defect incoming

so in your opinion, when two people with dwarfism try to marry, they should be stopped by the law for the very high risk of their offspring having dwarfism, is what you're telling us?

 

[Sheza]

The danger of inbreeding is more so in genetic disorders than birth defects.

Inbreeding between siblings greatly increases the chance of homozygousity for recessive genes. Harmful genes are usually recessive because that way they’re harder for natural selection to get rid of since they can be carried without harming the individual. In order for a recessive gene to be expressed you need a copy of it from both parents. If your parents are closely related then it is more likely for them to both have that recessive gene. Assuming that both parents are heterozygous for that harmful gene then the chance the child will have the disorder it causes Is 1/4.

Where inbreeding gets really bad is when you do it generation after generation. When you have a child you pass on only half of your genes. If you have another you aren’t guaranteed to pass on the opposite half, some of your genes probably won’t be passed on. Imagine a brother and sister having 2 children who then have 2 children and so on. Every generation some of the genes don’t get passed on and thus the genetic difference between them shrinks. Eventually everyone in this gene pool (more of a gene lane) will effectively be clones who are completely homozygous for everything and all harmful genetic disorders they still carry will be expressed.

tho continuous incest is totally safe when the parents themselves have no defective gene in the first place, it only gets dangerous when one descendant mutates a gene then pass that gene on to their offspring

 

[smormu]

tho continuous incest is totally safe when the parents themselves have no defective gene in the first place, it only gets dangerous when one descendant mutates a gene then pass that gene on to their offspring

what you seem to be describing is an inbred strain.

While you can have continuous brother sister pairings in an inbred strain if you have purged all genetic load, it has never been done with humans.

Inbred strains are used for research because having a population of genetically identical individuals is useful for consistency in tests. An inbred strain, for this example well use mice, is made by breeding two mice until you have about 100 offspring and picking out the very best male and female siblings and you cull the rest. You then breed the siblings until you get 100 offspring. Because they’re inbred many of them will be sickly or deformed, but some of them will be just fine. Once again you pick out the best male and female, breed them and repeat this process for at least 20 generations and you have an inbred strain. Inbred strains have basically zero genetic load and can inbreed without consequence indefinitely, but have worse immune systems due to their major histocompatability complex region DNA all being homozygous.

There are lots of problems with doing this with humans. Women have a very hard time having ten kids, let alone 100 so instead of picking out the best two of 100 you will be getting the best two of ten. Humans don’t like having 98% of their children killed. People take much longer to reach reproductive age meaning it would take centuries of continuous inbreeding to produce a human inbred strain.

Maybe with genetic engineering we’ll be able to make people with no genetic load without a multi century breeding program. There’s also embryo screening which could allow siblings to have children without risk.

 

[Sheza]

what you seem to be describing is an inbred strain.

While you can have continuous brother sister pairings in an inbred strain if you have purged all genetic load, it has never been done with humans.

Inbred strains are used for research because having a population of genetically identical individuals is useful for consistency in tests. An inbred strain, for this example well use mice, is made by breeding two mice until you have about 100 offspring and picking out the very best male and female siblings and you cull the rest. You then breed the siblings until you get 100 offspring. Because they’re inbred many of them will be sickly or deformed, but some of them will be just fine. Once again you pick out the best male and female, breed them and repeat this process for at least 20 generations and you have an inbred strain. Inbred strains have basically zero genetic load and can inbreed without consequence indefinitely, but have worse immune systems due to their major histocompatability complex region DNA all being homozygous.

There are lots of problems with doing this with humans. Women have a very hard time having ten kids, let alone 100 so instead of picking out the best two of 100 you will be getting the best two of ten. Humans don’t like having 98% of their children killed. People take much longer to reach reproductive age meaning it would take centuries of continuous inbreeding to produce a human inbred strain.

Maybe with genetic engineering we’ll be able to make people with no genetic load without a multi century breeding program. There’s also embryo screening which could allow siblings to have children without risk.

the way you said that in such an objective manner made me shiver

are you sure you're human and not a sentient AI observing humanity for the grand-take over of this planet?