I think when it comes to accent for the spider girl, American Southern would be a mistake. For one thing, I feel like American Southern is pretty established as "everyone uses that for Kansai accent". For another, nobody remembers about Southern belles any more; the connotations of Southern for most listeners are going to be kind of rural. You don't want to be doing something where you've got a sophisticated slightly archaic Kyoto girl and your rendering makes people think she should be wearing a MAGA hat.
I think the current approach is working well so far.