I think that the problem for Minami and Yuzu is that just as it's impossible to know what Yuzu is thinking, it's impossible for Yuzu to know what Minami is thinking. I mean, Minami is simping and going off into manic fits and the sexual come-ons may seem like part of that. How many times has Yuzu said to calm the hell down? Seriously, it's her signature line: "Slow down", "It's not right to push it too hard," etc. If Yuzu were interested in Minami romantically/sexually, wouldn't it be easy for her to think it's an element of Minami's weirdness? That it wouldn't be a good idea as long as her best friend is crazy?